In Nigeria, the dermatological application of azelaic acid cream is a frontline intervention for inflammatory acne. The 2026 supply chain in South Africa, Ghana, and Benin requires strict regulatory adherence to SAHPRA standards. The B2B procurers need to use a certified business-to-business network to reduce their operational risks. The benefits of azelaic acid provide essential support for Nigerian patients who need treatment for hyperpigmentation because the agent specifically targets their excessive melanin production. The authentic ezanic cream gel needs to be obtained through secure medical channels for successful clinical use.